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Adrenal Forte 120 vcaps


  • Promotes Healthy Response to Stress

    NEW & IMPROVED!!!   A comprehensive blend of the highest-quality adaptogenic herbs.  These ingredients aid in adrenal hormone production and support the body's adaptogenic response.  Also unlike many adrenal formulas on the market, Adrenal Forte is fully vegan.*

    A complete adrenal and adaptogenic solution in one bottle!  This formula incorporates the latest scientific research on nutrition and metabolic functions.  Individual nutrients are formulated for maximum bioavailability, synergy and hormonal activation.*  Specific features include:

    • Cordyceps sinensis (mycelium extract standardized to 7% cordycepic acids) - Both in vitro and in vivo animal studies have confirmed that Cordyceps sinensis helps stimulate adrenal function and promote healthy levels of cortisol production. One controlled, randomized human study showed that Cordyceps sinensis significantly reduced the pro-inflammatory biomarkers IgE, ICAM-1, IL-4, and MMP-9 while also reducing long-standing mild to moderate inflammatory lung conditions. Cordyceps is regarded as a very precious medicinal mushroom in China and other Asian countries. For over 2000 years, Cordyceps sinensis has been used as a tonic, to increase health and vitality, combat aging and help against various age-related diseases.  It is a safe, highly valued herb with activities that support nearly every physiological system impacted by the body’s response to normal everyday stressors, including the immune and cardiovascular systems. In addition the cell-protective and antioxidant activities of Cordyceps have been well documented.*

    • Rhodiola rosea (root extract standardized to 3% rosavin & 1% salidroside) - A number of studies have shown that Rhodiola can dramatically reduce mental and physical fatigue under stressful conditions by increasing the body’s energy levels.  It is believed that Rhodiola enhances the body’s tolerance to stress by influencing key brain chemicals, such as serotonin and norepinephrine, and natural feel-good opioids such as beta-endorphins. Recent studies reveal this herb's medicinal properties include anti-aging effects, anti-inflammatory effects and strong anti-stress effects. The main medical constituents of this herb  are eight in number, including rosarin, rosavin, rosin, salidroside, tyrosol, rhodionin, catechin and gallic acid. It also possesses several other significant antioxidants. Rodiola stimulates immunity, enhances DNA repair and modulates adaptation to hypoxia and angiogenesis.  According to a comprehensive review of the literature on Rhodiola, supplementation provides cognitive stimulation and supports healthy work performance, quality of sleep, emotional calming, appetite, and energy levels subsequent to intense physical or intellectual strain.*

    • Panax Ginseng - Red Ginseng (root extract standardized to 80% ginsenosides) - Studies show that ginseng and it content of ginsenosides have beneficial effects in supporting the adrenal glands and upregulates genes related to catecholamine production. The herbs also protects the gastric mucosa, and supports healthy body weight and an array of blood hormones. Ginsenosides also support the immune system and have cytokine-modulating activities. has been used in medicine for over 5000 years. In summary, Panax enhances athletic performance, and provides energy to people who are stressed or fatigued.*

    • Siberian ginseng - Eleutherococcus senticosus/Acanthopanax senticosus (root & stem extract standardized to 0.8% Eleutherosides B & E; ) - Is not actually ginseng, but rather a different plant species.  It contains eleutherosides and ciwujianosides as opposed to ginsenosides. Both stimulate cortisol production during exercise, energy and lessen fatigue. Additionally, this herb is well-known to support the immune system. Eleuthero has also been associated with increased mental ability, concentration and greater alertness.*

    • Ashwagandha - Withania somnifera  (root extract standardized to 1.5% Withanolides) - Aswagandha is one of the most vital herbs in Ayurvedic healing, has been used since ancient times for a wide variety of conditions, but is most well-known for its restorative benefits.  It is the ginseng of the Ayurvedic medicine.  A comprehensive cortisol study in mice revealed Ashwaganda extract reduced fatigue and increased stamina while increasing levels of circulating cortisol. One recent human clinical study showed that it promoted restoration to healthier levels four adrenal hormones. Specifically in this single case study, Ashwanganda helped normalize 3-β-ol dehydrogenase deficiency and aldosterone synthase deficiency. In general, the herb helps improve physical energy and athletic ability, increase immunity to those common winter challenges and increase sexual capacity and fertility.  Ashwaganda seems to show positive effects on the endocrine, cardio, and central nervous systems.  It is one herb that could help your body produce its own thyroid hormones.*

    Standard Dosage:  Take four capsules daily in divided doses or as directed by your healthcare practitioner. 

    *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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  • References

    1. Yue K, Ye M, Zhou Z, Sun W, Lin X. The Genus Cordyceps: A Chemical and Pharmacological Review. J Pharm Pharmacol. 2013 Apr;65(4):474-93. 
    2. Olatunji OJ, et al. The Genus Cordyceps: An Extensive Review of Its Traditional Uses, Phytochemistry and Pharmacology. Fitoterapia. 2018 May 24;pii:S0367-326X(18)30555-0.
    3. Leu SF, Chien CH, Tseng CY, Kuo YM, Huang BM. The in vivo effect of Cordyceps sinensis mycelium on plasma corticosterone level in male mouse. Biol Pharm Bull. 2005 Sep; 28(9):1722-5.
    4. Wang SM, Lee LJ, Lin WW, Chang CM. Effects of a water-soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplets in cultured rat adrenocortical cells. J Cell Biochem. 1998 Jun 15; 69(4):483-9.
    5. Wang N, Li J, Huang X, Chen W, Chen Y. Herbal Medicine Cordyceps sinensis Improves Health-Related Quality of Life in Moderate-to-Severe Asthma. Evid Based Complement Alternat Med. 2016; 2016: 6134593.
    6. Grech-Baran M, Syklowska-Baranek K, Pietrosiuk A. Approaches of Rhodiola kirilowii and Rhodiola rosea Field Cultivation in Poland and Their Potential Health Benefits. Ann Agric Environ Med. 2015;22(2):281-5.
    7. Panossian A, Wikman G, Sarris J. Rosenroot (Rhodiola rosea): Traditional Use, Chemical Compostion, Pharmacology and Clinical Efficacy. Phytomedicine. 2010 Jun;17(7):481-93.
    8. Jung DH, et al. Effects of Ginseng on Peripheral Blood Mitochondrial DNA Copy Number and Hormones in Men with Metabolic Syndrome: A Randomized Clinical and Pilot Study. Complement Ther Med. 2016 Feb;24:40-6.
    9. Kim SY, et al. Effects of Red Ginseng Supplementation on Menopausal Symptoms and Cardiovascular Risk Factors in Postmenopausal Women: A Double-Blind Randomized Controlled Trial. Menopause. 2012 Apr;19(4):461-6.
    10. Sellami M, et al. Herbal medicine for sports: a review. J Int Soc Sports Nutr. 2018; 15: 14.
    11. Ahuja A, Goswami A, Adhikari A, Ghosh AK. Evaluation of effects of revital on physical performance in sportsmenle. Indian Pr. 1992;45:685–688.
    12. Panossian A, Wikman G. Evidence-Based Efficacy of Adaptogens in Fatigue, and Molecular Mechanisms Related to Their Stress-Protective Activity. Curr Clin Pharmacol. 2009 Sep;4(3):198-219.
    13. Panossian A, Wikman G. Effects of Adaptogens on the Central Nervous Center System and the Molecular Mechanisms Associated with Their Stress-Protective Activity. Pharmaceuticals (Basel). 2010 Jan;3(1):188-224.
    14. Rege NN, Thatte UM, Dhanukar SA. Adaptogenic Properties of Six Rasayana Herbs Used in Ayurvedic Medicine. Phytother Res. 1999 Jun;13(4):275-91.
    15. Singh B, et al. Adaptogenic activity of a novel, withanolide-free aqueous fraction from the roots of Withania somnifera Dun. Phytother Res. 2001 Jun; 15(4):311-8.
    16. Singh B, Chandan BK, Gupta DK. Adaptogenic activity of a novel withanolide-free aqueous fraction from the roots of Withania somnifera Dun. (Part II). Phytother Res. 2003 May; 17(5):531-6.
    17. Kalani A, et al. Ashwagandha root in the treatment of non-classical adrenal hyperplasia. . 2012; 2012: bcr2012006989.

    18. Sudhir S, Budhiraja RD. Comparison of the Protective Effect of Withanferin-A and Hydrocortisone Against CCL4 Induced Hepatotoxicity in Rats. Indian J Physiol Pharmacol. 1992 Apr;36(2):127-9.



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